Immunological Sciences

MYBBP1A (14I6) Rabbit Monoclonal Antibody

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Catalog Number:MABN14262
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MYBBP1A
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:200-1:500,FC 1:50-1:100
Molecular Weight:149kDa
Purification:Affinity purification
Form:Liquid
Synonyms:cb486; Mybbp1a; P160; p160MBP; p67MBP; PAP2; RP23 48A2.3;

Applications

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:200-1:500,FC 1:50-1:100

Immunogen

A synthetic peptide of human MYBBP1A

Target Background

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309).

Synonyms:cb486; Mybbp1a; P160; p160MBP; p67MBP; PAP2; RP23 48A2.3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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