Immunological Sciences

NACAD Rabbit Polyclonal Antibody

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Catalog Number:ABN14390
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300
Molecular Weight:140kDa
Purification:Affinity purification
Form:Liquid
Synonyms:NACAD; KIAA0363; NAC-alpha domain-containing protein 1

Applications

WB 1:500-1:2000,IHC 1:50-1:300

Immunogen

The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425

Target Background

function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,

Synonyms:NACAD; KIAA0363; NAC-alpha domain-containing protein 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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