Immunological Sciences

NDRG1 (3L1) Rabbit Monoclonal Antibody

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Catalog Number:MABN14475
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human NDRG1
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:10000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50
Molecular Weight:43kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Protein NDRG1; Differentiation-related gene 1 protein; DRG-1; RTP; Rit42; NDRG1; CAP43; DRG1; RTP; targ1; TDD5; tdds;

Applications

WB 1:2000-1:10000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human NDRG1

Target Background

May have a growth inhibitory role. Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy.

Synonyms:Protein NDRG1; Differentiation-related gene 1 protein; DRG-1; RTP; Rit42; NDRG1; CAP43; DRG1; RTP; targ1; TDD5; tdds;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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