Immunological Sciences

NDUFA1 Rabbit Monoclonal Antibody

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Catalog Number:MABN21237
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human NDUFA1
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:300,IP 1:50-1:100
Molecular Weight:CalcuLated MW:;Observed MW:8kD
Purification:Protein A
Form:Liquid
Synonyms:NDUFA1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 ;Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit;

Applications

WB 1:1000-1:5000,IHC 1:100-1:300,IP 1:50-1:100

Immunogen

A synthetic peptide of human NDUFA1

Target Background

Cell localization:Mitochondrion inner membrane; Single-pass membrane protein; Matrix side..The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],

Synonyms:NDUFA1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 ;Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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