Immunological Sciences

Nectin 2 (11O15) Rabbit Monoclonal Antibody

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Catalog Number:MABN14530
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Nectin 2
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:50-1:100,IF-P 1:50-1:100
Molecular Weight:58kDa
Purification:Affinity purification
Form:Liquid
Synonyms:HVEB; PRR2; CD112; PVRR2;

Applications

WB 1:500-1:2000,IHC 1:50-1:100,IF-P 1:50-1:100

Immunogen

Recombinant protein of human Nectin 2

Target Background

Probable cell adhesion protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005).

Synonyms:HVEB; PRR2; CD112; PVRR2;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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