Immunological Sciences

Nesprin 3 Rabbit Monoclonal Antibody

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Catalog Number:MABN84075
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human Nesprin 3
Reactivity:Human
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 112 kDa ; Observed MW: 100 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:C14orf49; Nesp3; Nesprin 3; NET53; SYNE3;;Nesprin 3

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human Nesprin 3

Target Background

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

Synonyms:C14orf49; Nesp3; Nesprin 3; NET53; SYNE3;;Nesprin 3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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