Immunological Sciences

Neuregulin 1 SMDF Rabbit Polyclonal Antibody

Western blot analysis of lysates from SKOV3 cells, using NRG1 isoform-10 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from SKOV3 cells, using NRG1 isoform-10 Antibody. The lane on the right is blocked with the synthesized peptide.

Catalog Number:AB-81704
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:POLY
Immunogen:The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50
Reactivity:Human, Mouse, Rat
Applications:Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000
Molecular Weight:44kD
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form:Liquid
Synonyms:Pro-neuregulin-1 membrane-bound isoform; Pro-NRG1; NRG1; GGF; HGL; HRGA; NDF; SMDF

Applications

Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000

Immunogen

The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50

Target Background

The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing.These isoforms are expressed in a tissue-specific manner and differ significantly in their structure,and are classified as types I, II, III, IV, V and VI.Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Synonyms:Pro-neuregulin-1 membrane-bound isoform; Pro-NRG1; NRG1; GGF; HGL; HRGA; NDF; SMDF

Storage

Store at -20°C. Avoid repeated freeze-thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western blot analysis of lysates from SKOV3 cells, using NRG1 isoform-10 Antibody. The lane on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embeddedhuman brain tissue, using NRG1 isoform-10 Antibody. The picture on the right is blocked with the synthesized peptide.

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