Immunological Sciences

NFE2 (14H9) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN14645
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Nuclear Factor Erythroid Derived 2
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:100-1:200,FC 1:200-1:500,IF-P 1:100-1:200
Molecular Weight:41kDa
Purification:Affinity purification
Form:Liquid
Synonyms:nfe2 ; Nuclear factor; p45 NFE2;

Applications

WB 1:500-1:2000,IHC 1:100-1:200,FC 1:200-1:500,IF-P 1:100-1:200

Immunogen

Recombinant protein of human Nuclear Factor Erythroid Derived 2

Target Background

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1- like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Synonyms:nfe2 ; Nuclear factor; p45 NFE2;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.