Immunological Sciences

NFKBIB Mouse Monoclonal Antibody

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Catalog Number:MABN80875
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human NFKBIB expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:45kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IKBB; TRIP9; NFKBIB

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human NFKBIB expressed in E. Coli.

Target Background

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

Synonyms:IKBB; TRIP9; NFKBIB

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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