Nicastrin Rabbit Monoclonal Antibody

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Catalog Number:MABN85858
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Nicastrin
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IP 1:10-1:20
Molecular Weight:Calculated MW: 78 kDa; Observed MW: 110-120 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:APH2; Ncstn; NCT; Nicastrin

Applications

WB 1:500-1:1000,IP 1:10-1:20

Immunogen

A synthetic peptide of human Nicastrin

Target Background

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Synonyms:APH2; Ncstn; NCT; Nicastrin

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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