Immunological Sciences

NMDA Receptor 2A

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Catalog Number:AB-10146
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:POLY
Reactivity:Hu, Ms, Rt
Applications:Western Blot: 1:500 -1:2000Immunohistochemistry: 1:50 -1:200Immunofluorescence: 1:50 -1:200
Molecular Weight:160kDa
Purification:Aff. Pur.
Form:Liquid
Synonyms:GRIN2A; EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A ; glutamate receptor ionotropic, NMDA 2A
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Applications

Western Blot: 1:500 -1:2000Immunohistochemistry: 1:50 -1:200Immunofluorescence: 1:50 -1:200

Target Background

This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Synonyms:GRIN2A; EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A ; glutamate receptor ionotropic, NMDA 2A

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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