Immunological Sciences

nNOS (neuronal) Rabbit Monoclonal Antibody

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Catalog Number:MABN87245
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human nNOS (neuronal)
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:100-1:200
Molecular Weight:Calculated MW:161 kDa; Observed MW:161 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS

Applications

WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:100-1:200

Immunogen

A synthetic peptide of human nNOS (neuronal)

Target Background

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]

Synonyms:NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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