Immunological Sciences

non-muscle Myosin IIA Rabbit Monoclonal Antibody

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Catalog Number:MABN86526
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human non-muscle Myosin IIA
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:10-1:100
Molecular Weight:Calculated MW:227 kDa; Observed MW:227 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MHA; FTNS; EPSTS; BDPLT6; DFNA17; NMMHCA; NMHC-II-A; NMMHC-IIA

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:10-1:100

Immunogen

A synthetic peptide of human non-muscle Myosin IIA

Target Background

This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]

Synonyms:MHA; FTNS; EPSTS; BDPLT6; DFNA17; NMMHCA; NMHC-II-A; NMMHC-IIA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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