NOXA Rabbit Monoclonal Antibody

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Catalog Number:MABN02829
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Noxa
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 6 kDa; Observed MW: 10 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:APR; ATL-derived; NOXA; Pmaip1; Protein Noxa

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human Noxa

Target Background

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Synonyms:APR; ATL-derived; NOXA; Pmaip1; Protein Noxa

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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