Immunological Sciences

NPC1L1 Rabbit Monoclonal Antibody

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Catalog Number:MABN84373
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human NPC1L1
Reactivity:Human
Applications:WB 1:1000-1:2000
Molecular Weight:149 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NPC1 LIKE 1; NPC1L1;;NPC1L1

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human NPC1L1

Target Background

Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia.

Synonyms:NPC1 LIKE 1; NPC1L1;;NPC1L1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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