Immunological Sciences

NQO1 Rabbit Monoclonal Antibody

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Catalog Number:MABN21489
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human NQO1
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:31kD;Observed MW:31kD
Purification:Protein A
Form:Liquid
Synonyms:NQO1;DIA4;NMOR1;NAD;P;H dehydrogenase [quinone] 1;Azoreductase;DT-diaphorase;DTD;Menadione reductase;NAD;P;H:quinone oxidoreductase 1;Phylloquinone reductase;Quinone reductase 1;QR1

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human NQO1

Target Background

Cell localization:Cytoplasm.This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Synonyms:NQO1;DIA4;NMOR1;NAD;P;H dehydrogenase [quinone] 1;Azoreductase;DT-diaphorase;DTD;Menadione reductase;NAD;P;H:quinone oxidoreductase 1;Phylloquinone reductase;Quinone reductase 1;QR1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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