Immunological Sciences

NRCAM Mouse Monoclonal Antibody

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Catalog Number:MABN81211
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. Coli.
Reactivity:Human
Applications:ICC 1:20-1:50,ELISA 1:5000-1:20000
Molecular Weight:144kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NRCAM

Applications

ICC 1:20-1:50,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. Coli.

Target Background

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms:NRCAM

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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