Immunological Sciences

NrCAM Rabbit Monoclonal Antibody

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Catalog Number:MABN86799
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human NrCAM
Reactivity:Human
Applications:WB 1:2000-1:20000,IHC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:144 kDa; Observed MW:144 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:KIAA0343

Applications

WB 1:2000-1:20000,IHC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human NrCAM

Target Background

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Synonyms:KIAA0343

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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