NRG3 Rabbit Monoclonal Antibody

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Catalog Number:MABN02356
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human NRG3
Reactivity:Human,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 78 kDa; Observed MW: 55 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NRG3; Pro-neuregulin-3; membrane-bound isoform; Pro-NRG3

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human NRG3

Target Background

Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

Synonyms:NRG3; Pro-neuregulin-3; membrane-bound isoform; Pro-NRG3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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