Immunological Sciences

NT-3 Rabbit Polyclonal Antibody

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Catalog Number:ABN14917
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthetic peptide from human protein at AA range: 180-230
Reactivity:Human,Mouse,Rat
Applications:IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:Neurotrophin-3 (NT-3;HDNF;Nerve growth factor 2;NGF-2;Neurotrophic factor)

Applications

IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

Immunogen

Synthetic peptide from human protein at AA range: 180-230

Target Background

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008],function:Seems to promotes the survival of visceral and proprioceptive sensory neurons.,polymorphism:Variant Glu-76 (frequently reported as Glu-63) was thought to be associated with severe forms of schizophrenia. This does not seem to be the case.,similarity:Belongs to the NGF-beta family.,tissue specificity:Brain and peripheral tissues.,

Synonyms:Neurotrophin-3 (NT-3;HDNF;Nerve growth factor 2;NGF-2;Neurotrophic factor)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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