Occludin Rabbit Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using Occludin antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti- Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL West Pico Plus Exposure time: 1s.
| Catalog Number: | AB-83608 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Clone: | POLY |
| Immunogen: | Recombinant protein of human OCLN |
| Reactivity: | Hu, Ms ,Rt |
| Applications: | WB 1:1000 - 1:2000IHC 1:50 - 1:200IF 1:50 - 1:200 |
| Molecular Weight: | 59kDa |
| Purification: | Aff. Pur. |
| Form: | Liquid |
| Synonyms: | None |
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. RRID AB_2764486 Gene ID 100506658 Swiss Prot Synonym BLCPMG; PTORCH1; PPP1R115; Occludin
Applications
WB 1:1000 - 1:2000IHC 1:50 - 1:200IF 1:50 - 1:200
Immunogen
Recombinant protein of human OCLN
