Immunological Sciences

Oct1(7G1)Mouse Monoclonal Antibody

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Catalog Number:MABN15099
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG
Clone:Monoclonal
Immunogen:Synthetic Peptide of 42644
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:50-1:300,ICC/IF 1:100-1:200
Molecular Weight:89kDa
Purification:Affinity purification
Form:Liquid

Applications

WB 1:500-1:2000,IHC 1:50-1:300,ICC/IF 1:100-1:200

Immunogen

Synthetic Peptide of 42644

Target Background

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010],function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.,PTM:Phosphorylated by PRKDC.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR, PGR and HCFC1.,tissue specificity:Ubiquitous. Isoform 2 is lymphocyte-specific.,

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.

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