Immunological Sciences

OPA1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86943
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human OPA1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500
Molecular Weight:Calculated MW:112 kDa; Observed MW:80 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NPG; NTG; MGM1; BERHS; largeG; MTDPS14

Applications

WB 1:1000-1:5000,IHC 1:200-1:500

Immunogen

A synthetic peptide of human OPA1

Target Background

The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017]

Synonyms:NPG; NTG; MGM1; BERHS; largeG; MTDPS14

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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