OPA1 Rabbit Monoclonal Antibody
Western blot analysis of OPA1 in HeLa, A431 lysates using OPA1 antibody.
| Catalog Number: | MABN03939 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human OPA1 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100 |
| Molecular Weight: | Observed MW: 80 kDa |
| Purification: | Affinity Purification |
| Form: | Liquid |
| Synonyms: | Large GTP binding protein; largeG; MGM1; Mitochondrial dynamin like GTPase; NPG; NTG; OAK; OPA 1 |
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Applications
WB 1:500-1:1000,IHC 1:50-1:100
Immunogen
A synthetic peptide of human OPA1