Immunological Sciences

ORC5 Rabbit Polyclonal Antibody

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Catalog Number:ABN15499
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from part region of human protein
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:47kDa
Purification:Affinity purification
Form:Liquid

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Synthesized peptide derived from part region of human protein

Target Background

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Oct 2010],function:Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner.,similarity:Belongs to the ORC5 family.,subunit:ORC is composed of six subunits.,

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

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