Immunological Sciences

Orexin R-1 Rabbit Polyclonal Antibody

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Catalog Number:ABN15503
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human HCRTR1. AA range:231-280
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:10000
Molecular Weight:50kDa
Purification:Affinity purification
Form:Liquid
Synonyms:HCRTR1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1

Applications

WB 1:500-1:2000,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human HCRTR1. AA range:231-280

Target Background

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009],function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Synonyms:HCRTR1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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