Immunological Sciences

Osteoprotegerin Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN86262
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Osteoprotegerin
Reactivity:Human
Applications:IHC 1:100-1:200,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW:46 kDa; Observed MW:
Purification:Affinity Purification
Form:Liquid
Synonyms:OPG; TR1; OCIF; PDB5

Applications

IHC 1:100-1:200,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human Osteoprotegerin

Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Synonyms:OPG; TR1; OCIF; PDB5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.