OTC Rabbit Polyclonal Antibody

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Catalog Number:ABN00348
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human Ornithine Carbamoyltransferase
Reactivity:Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 40 kDa; Observed MW: 40 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD

Applications

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of human Ornithine Carbamoyltransferase

Target Background

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Synonyms:OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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