p38 Rabbit Monoclonal Antibody

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Catalog Number:MABN21421
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide corresponding to target protein
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:41kD;Observed MW:41kD
Purification:Protein A
Form:Liquid
Synonyms:Mitogen-activated protein kinase 14;MAP kinase 14;MAPK 14;Cytokine suppressive anti-inflammatory drug-binding protein;CSAID-binding protein;CSBP;MAP kinase MXI2;MAX-interacting protein 2;Mitogen-activated protein kinase p38 alpha;MAP kinase p38 alpha;Stress-activated protein kinase 2a;SAPK2a;

Applications

WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide corresponding to target protein

Target Background

Cell localization:Cytoplasm, Nucleus.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d

Synonyms:Mitogen-activated protein kinase 14;MAP kinase 14;MAPK 14;Cytokine suppressive anti-inflammatory drug-binding protein;CSAID-binding protein;CSBP;MAP kinase MXI2;MAX-interacting protein 2;Mitogen-activated protein kinase p38 alpha;MAP kinase p38 alpha;Stress-activated protein kinase 2a;SAPK2a;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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