Immunological Sciences

p57 Kip2 Rabbit Monoclonal Antibody

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Catalog Number:MABN03136
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human p57 Kip2
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 32 kDa; Observed MW: 57 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2

Applications

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of human p57 Kip2

Target Background

p27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.

Synonyms:CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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