Immunological Sciences

p73 (8W9) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN15668
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human p73
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:70kDa
Purification:Affinity purification
Form:Liquid
Synonyms:p53-like transcription factor; p53-related protein; P73 alpha protein; p73-alpha; TP73; TRP73; Tumor protein p73;

Applications

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human p73

Target Background

p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described. Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Synonyms:p53-like transcription factor; p53-related protein; P73 alpha protein; p73-alpha; TP73; TRP73; Tumor protein p73;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.