p73 Rabbit Monoclonal Antibody

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Catalog Number:MABN03974
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human p73
Reactivity:Human, Mouse
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100
Molecular Weight:Calculated MW:70 kDa;Observed MW: 70,60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100

Immunogen

Recombinant protein of human p73

Target Background

p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.

Synonyms:TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

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