p73 Rabbit Monoclonal Antibody

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Catalog Number:MABN85900
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human p73
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:10-1:20
Molecular Weight:Calculated MW: 70 kDa; Observed MW: 80,70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Applications

WB 1:500-1:1000,IP 1:10-1:20

Immunogen

A synthetic peptide of human p73

Target Background

p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.

Synonyms:TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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