PAF1 Rabbit Monoclonal Antibody

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Catalog Number:MABN84360
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human PAF1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 60 kDa ; Observed MW: 80 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:hPAF1; PAF1; PD2;;PAF1

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human PAF1

Target Background

Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1.

Synonyms:hPAF1; PAF1; PD2;;PAF1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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