Immunological Sciences

PAI1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87591
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse PAI1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW:45 kDa; Observed MW:45 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PAI; PAI1; PAI-1; PLANH1

Applications

WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:100,IP 1:20-1:50

Immunogen

Recombinant protein of mouse PAI1

Target Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Synonyms:PAI; PAI1; PAI-1; PLANH1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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