PARK7/DJ1 Rabbit Monoclonal antibody

Western blot analysis of PARK7/DJ1 in K562, rat Brain, C6, 3T3, Hela lysates using PARK7/DJ1 antibody.

Western blot analysis of PARK7/DJ1 in K562, rat Brain, C6, 3T3, Hela lysates using PARK7/DJ1 antibody.

Catalog Number:MABN01508
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Immunogen:A synthetic peptide of human PARK7/DJ1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:20 kDa
Purification:Affinity purification
Form:liquid
Synonyms:PARK7; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7

Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress.

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human PARK7/DJ1

Target Background

Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress.

Synonyms:PARK7; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Western blot analysis of PARK7/DJ1 in K562, rat Brain, C6, 3T3, Hela lysates using PARK7/DJ1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using PARK7/DJ1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of PARK7/DJ1 (green) in Hela using PARK7/DJ1 antibody, and DAPI (blue)

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