PARK7/DJ1 Rabbit Monoclonal Antibody

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Catalog Number:MABN85193
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PARK7/DJ1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight:Calculated MW: 20 kDa; Observed MW: 20 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PARK7; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20

Immunogen

A synthetic peptide of human PARK7/DJ1

Target Background

Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress.

Synonyms:PARK7; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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