Immunological Sciences

Parkin (17H13) Rabbit Monoclonal Antibody

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Catalog Number:MABN15758
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Parkin
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000
Molecular Weight:52kDa
Purification:Affinity purification
Form:Liquid
Synonyms:AR-JP; LPRS2; PARK2; parkin; parkin 2; PDJ; PRKN; PRKN2;

Applications

WB 1:500-1:2000

Immunogen

Recombinant protein of human Parkin

Target Background

Parkin is a zinc-finger protein that is related to ubiquitin at the amino terminus. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. Regulates cyclin-E during neuronal apoptosis. Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Synonyms:AR-JP; LPRS2; PARK2; parkin; parkin 2; PDJ; PRKN; PRKN2;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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