Parkin / Park 2 Rabbit Polyclonal Antibody
SH-SY5Y cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with Parkin Rabbit Polyclonal Antibody 1:1000. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
| Catalog Number: | ABN21149 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml. The concentration of this product may be batch-dependent. |
| Host: | Rabbit |
| Isotype: | IgG,Kappa |
| Immunogen: | Recombinant protein of human Parkin |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:2000-1:10000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
| Molecular Weight: | 52kD |
| Purification: | Protein A |
| Form: | Liquid |
| Synonyms: | PARK2;PRKN;E3 ubiquitin-protein ligase parkin;Parkinson juvenile disease protein 2;Parkinson disease protein 2 |
Cell localization:Cytoplasm.The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
Applications
WB 1:2000-1:10000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Immunogen
Recombinant protein of human Parkin
