PARP1 Rabbit Monoclonal Antibody
Western blot analysis of PARP1 in K562, 3T3, Hela lysates using PARP1 antibody.
| Catalog Number: | MABN02401 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1 mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Monoclonal |
| Immunogen: | A synthetic peptide of human PARP |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 |
| Molecular Weight: | Observed MW: 116,89 kDa |
| Purification: | Affinity Purification |
| Form: | Liquid |
| Synonyms: | PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1 |
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Applications
WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200
Immunogen
A synthetic peptide of human PARP
