PAX3 Mouse Monoclonal Antibody
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
| Catalog Number: | MABN83076 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli. |
| Reactivity: | Human,Mouse |
| Applications: | WB 1:500-1:2000,ELISA 1:5000-1:20000 |
| Molecular Weight: | 53kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | WS1; WS3; CDHS; HUP2 |
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Applications
WB 1:500-1:2000,ELISA 1:5000-1:20000
Immunogen
Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli.
