PBEF1 Mouse Monoclonal Antibody

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Catalog Number:MABN80633
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.
Reactivity:Human, Rat, Mouse, Monkey, Rabbit
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:55kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:VF; PBEF; PBEF1; VISFATIN; NAMPT

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.

Target Background

PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Synonyms:VF; PBEF; PBEF1; VISFATIN; NAMPT

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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