PCGF6 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87596
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse PCGF6
Reactivity:Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW:40 kDa; Observed MW:40 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MBLR; Rnf134; AI604840; 4933407A11Rik

Applications

WB 1:500-1:2000,ICC/IF 1:100-1:200,IP 1:20-1:50

Immunogen

Recombinant protein of mouse PCGF6

Target Background

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.

Synonyms:MBLR; Rnf134; AI604840; 4933407A11Rik

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.