PCNA Mouse Monoclonal Antibody

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Catalog Number:MABN83030
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli.
Reactivity:Human,Mouse,Rat,Rabbit,Monkey
Applications:WB 1:500-1:2000,IHC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:28.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PCNA

Applications

WB 1:500-1:2000,IHC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli.

Target Background

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Synonyms:PCNA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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