Immunological Sciences

PCNA Rabbit Monoclonal Antibody

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Catalog Number:MABN86357
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PCNA
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:100
Molecular Weight:Calculated MW:29 kDa; Observed MW:36 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ATLD2

Applications

WB 1:500-1:2000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human PCNA

Target Background

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Synonyms:ATLD2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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