PCPTP1 Rabbit Monoclonal antibody

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Catalog Number:MABN02408
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PCPTP1
Reactivity:Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 74 kDa; Observed MW: 74 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human PCPTP1

Target Background

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus .

Synonyms:PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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