Immunological Sciences

CDX2 (14H6) Mouse Monoclonal Antibody

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Catalog Number:MABN05895
Conjugate:unconjugated
Size:100 μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG
Clone:14H6
Immunogen:CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2
Reactivity:Species, Human
Applications:WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200
Molecular Weight:42kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2
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Applications

WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200

Immunogen

CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Target Background

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.

Synonyms:CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles

Buffer

PBS, pH 7.4, containing 0.5%protective protein, 0.02% New type preservative N as Preservative and 50% Glycerol.

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