PDE1B Mouse Monoclonal Antibody

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Catalog Number:MABN83049
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli.
Reactivity:Human,Mouse,Monkey
Applications:ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:61.4kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PDE1B1; PDES1B

Applications

ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli.

Target Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms:PDE1B1; PDES1B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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