Immunological Sciences

PDE3A Rabbit Monoclonal Antibody

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Catalog Number:MABN86327
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human PDE3A
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IP 1:10-1:100
Molecular Weight:Calculated MW:125 kDa; Observed MW:125 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HTNB; CGI-PDE; CGI-PDE A; CGI-PDE-A

Applications

WB 1:1000-1:5000,IP 1:10-1:100

Immunogen

Recombinant protein of human PDE3A

Target Background

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Synonyms:HTNB; CGI-PDE; CGI-PDE A; CGI-PDE-A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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