PDGFRA Mouse Monoclonal Antibody
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
| Catalog Number: | MABN81415 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli. |
| Reactivity: | Human,Mouse,Monkey |
| Applications: | ICC 1:50-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight: | 7kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | CD140A; PDGFR2; PDGFR-2; RHEPDGFRA |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Applications
ICC 1:50-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400
Immunogen
Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.
